Oleander Extract

Dr H. Zima Ozel and Oleander Extract

In 1966, a Turkish doctor named H. Zima Ozel discovered a group of rural Turkish villagers that he claims were living amazingly healthy and disease-free lives compared to similar cultures in the area. When he investigated further, he found that the villagers were taking a natural folk remedy that had been used in the Middle East for over 2000 years.  It comes from a plant that is referred to in the Bible as “the Desert Rose,” or more commonly known as Oleander.

The term “oleander” refers to two plant species, Nerium oleander (common oleander) and Thevetia peruviana (yellow oleander). Both species contain chemicals called “cardiac glycosides” which have toxic effects when handled or ingested in its raw state, but when properly prepared and diluted, the Oleander extract is said to only be toxic to cancerous cells, yet harmless to normal cells.

Dr Ozel later created his own variation of the recipe that was based on the original formula and has sold it under the name of Anvirzel for the past 40 years.  Dr Ozel claims that Anivirzel can be used by those with cancer, hepatitis-C, HIV-AIDS, psoriasis, and other degenerative diseases, with the best results said to be for cancer of the prostate, lung, and brain, along with the stabilization of sarcomasAlthough the product initially passed FDA phase 1 trials and has been used successfully in hospitals and clinics outside of the USA, it may be many more years before Anvirzel™ or any other Oleander extract is ever approved for use in the United States


News report on using Oleander as a treatment for cancer

Link to the first in-human study: using oleander on patients with advanced solid tumor cancers

Oleander supplements can be ordered online or you can make your own oleander extract with the recipe below.

Cancer Tutor recommends Rose Laurel Complex along with some additional supplements which they state are needed for better absorption of the product and can be found here: online vendor of Rose Laurel (Oleander)_Complex

Recipe to make your own Oleander Extract

Note all of the contraindications and cautions related to this recipe and read through all of the resources at the bottom of the page before attempting to handle oleander.

If you have access to the Oleander plant then you can make your own extract very inexpensively. This recipe is based on the original one used by Doctor Ozel and was obtained from the research that he did in the Middle East.  Oleander can be found  growing in the southern and southwestern United States, and throughout much of the world. If it isn’t growing naturally near you, the plant can shipped through many mail-order nurseries over the internet.   Please note that it is important to have access to plants that have not been sprayed with pesticides or other chemicals when purchasing them to make this extract.

Because of its toxicity Oleander should always be handled with gloves, and because of the precautions relating to handling and ingesting, it is highly recommended that you read Tony Isaacs book Cancer’s Natural Enemy before attempting to make your own extract. 

Materials Needed:

  • Rubber gloves
  • Garden Trimmers (such a rose trimmer)
  • Plastic trash bag or a large plastic shopping bag
  • Large cooking pot
  • 4 plastic or metal strainers (colanders)
  • Unbleached coffee filters or paper towels
  • Steel tongs and/or steel strainer-type cooking ladle
  • Soup ladle
  • 20-ounce bottles or brown glass bottles with lids
  • 80 proof vodka or raw apple cider vinegar such as Bragg Organic Raw Apple Cider Vinegar which is used as a preservative.

Recipe to make your own oleander extract:

1. Wear rubber gloves to trim the new growth from the oleander plants that will be about 6″ from the tips.  Any part of the plant can be used including the stems, and leaves.  Trimming the new growth at the 6″ size will ensure that the plant survives the trimming and that the trimmings will easily fit into your cooking pot.

2. Rinse the cuttings outside with a hose and then put the trimmings into a plastic shopping bag or directly into your large cooking pot as described in step 3.  It is very important to avoid touching the cut ends, and to wear your gloves as the sap can penetrate the skin and it is toxic. 

3. Use a large porcelain or stainless steel pot only, one that fits up to 12 quarts, and then add your trimmings to the pot.  Fill with water to cover all of the trimmings and then pack the oleander down so that it is flat against the bottom of the pan.  Make sure the water level is at least two inches from the top to help prevent a boil over and that all of the oleander pieces are fully submerged into the water.

4.  Do not stir this mixture while it cooks, but you do want to monitor the pot to prevent a boil over.  Place a lid onto the pot and cook at a low boil for at least 3.5 to 4 hours.

5. After cooking for 3.5 to 4 hours you should remove all of the plant materials from the pot with a tongs or with a straining ladle and then discard them, being careful not to spill the liquid onto yourself as it will be hot. The remaining liquid volume should be about 60 to 70% of the original liquid.

6. The next step is to boil the remaining liquid for an additional 3 hours. This will reduce the liquid by an additional 50%, so you will end up with about 30% of the original liquid volume.   Let this liquid cool to room temperature while sitting covered for about two or more hours. This liquid should be as thick as a soup broth. It is important not to stir the mixture as you want the sediment to remain at the bottom of the pot when you remove the liquid with a ladle.  All sediment is to be discarded in the next step.

7. Using a ladle you will strain the liquid through 4 layers of large and preferably unbleached coffee filters, interchanged with colanders. (like this: colander/ filter/colander/filter/colander/filter/colander/filter). Stack one on top of another with a coffee filter (or a paper towel) in between each layer.  These should be placed over a large pan or bowl to collect the liquid. The top filter (or towel) may plug with debris and will need to be replaced as you are filtering. Use  a soup ladle to slowly pour the liquid through the towels, straining into a two-quart pan or into a large bowl.  You do  not want to pour directly from the pan as you want all of the sediment to remain at the bottom of the pan to be discarded.

8. Repeat this same filtering process for a second time, once again pouring through four layers of unbleached coffee filters that have been set into four colanders.  The original instructions did not call for this additional filtration, however, it has been determined that the additional filtration is needed to remove any organic compounds that commonly cause side-effects to those taking this therapy.

9. To preserve the filtered product: you will mix the liquid with equal parts of 80 proof vodka (preferred) or with the Bragg Organic Raw Apple Cider Vinegar which should extend the shelf life of this mixture for at least 6 months.

10. Use a funnel and pour into 20 oz empty glass bottles with tight lids, or into Amber Bottles and then refrigerate the finished product.  Avoid direct sunlight on the final liquid as it will degrade if exposed to light.

Oleander Dosage:

  • You will need to add a concentrated organic flavoring (such as grape juice) to the individual dosage that you take, but do not use anything which contains added sugar, high fructose corn syrup or artificial sweetener.
  • Begin this therapy slowly by taking 1/4 of a tsp after a meal, taken only once per day.
  • then build yourself up to taking ¼  teaspoon, two times per day after your meals.
  • You will then build up to taking the 1/4 tsp, 3 times per day after your meals
  • Then try to increase that dosage to 1/2 tsp,  taken 2 or 3 times per day after your meals.
  • If you can tolerate this, then you can continue to work up your dosage, once again going slowly until you reach the recommended dosage of 1 tablespoon, taken three times per day after your meals.  It may take weeks to reach this dosage.
  • It should also be noted that anyone with cancer needs to be on an anti-cancer diet that promotes good health.

Maintenance dose– once a disease such as cancer is brought under control there is always a risk of recurrence   Therefore continuation of a smaller maintenance dosage should be considered  This would consist of one regular dose of 1 tbsp  taken  three times per week, taken after your  meals.  Keeping up with a maintenance dose would be easy to do if you have access to the plant, thus making the soup relatively easy to make and cost efficient as well.   It is believed that long-term usage boosts the immune system, helps prevent many diseases, and targets only cancerous cells.

Side effects-  are usually mild and will vary from one person to another, with some people reporting little or no side effects at all.  Typical side effects by those who have reported them include: mild fever, headache, diarrhea, nausea and sometimes vomiting.  Usually these go away in a couple of week as the body begins to adjust to the oleander extract. To counter diarrhea, many oleander users report that they take an over-the-counter diarrhea control medicine such as Imodium.

After a month or so of taking oleander you should be near the full dose (1 Tablespoon taken 3 times per day, after your meal) with minimum reactions.  Note:  It is strongly believed that the key to avoiding most, if not all, side effects is giving the soup the extra filtration that is mentioned above.

Pesticide contamination–  it is also imperative that the oleander that one uses to make the extract is not contaminated with pesticides or other chemicals.  If pesticide contamination is present this may cause a tingling or numbing sensation when the extract touches the lips, therefore, any soup that produces this sensation should be discarded. 


Because this is an extract that acts similar to digitalis (which makes your heart work harder). those with heart conditions or high blood pressure should only use oleander soup under the care of their doctor, and preferably that doctor is someone  familiar with integrative medicine.

Most herbals can be taken with oleander extract except for foxglove (digoxin/ digitalis) which alsocontains the cardiac glycosides.  The product is compatible with virtually all medications, including chemotherapy, with the exception of blood thinning agents such as Warfarin and Coumadin.  In which case it should be used with caution and under the direction of a medical professional.

It is important to stress that anyone who makes the home version should read through all of the instructions and precautions in the resources before handling oleander, and they should purchase Tony Isaacs eBook Oleander: Cancer’s Natural Enemy before attempting this therapy.
Please read through all resources before using this therapy:

Combine this therapy with a healing diet and lifestyle changes

Cancer is a wake up call which needs to be addressed on multiple fronts.   It is the result of an overly toxic body with an overwhelmed and collapsed immune system due to eating nutritionally depleted diets and having poor lifestyle habits. Research an anticancer diet, adding supplements, detoxing the body, and making lifestyle changes so you can address a cancerous situation with a multifaceted approach.

Read more about an anticancer diet
Cancer cannot survive in an alkaline oxygenated environment
Read more about an alkaline diet
Read about sugar and cancer
Various detoxing therapies