Enzyme Therapy (Systemic)

Enzymes are natural proteins that stimulate and accelerate various biological reactions in the body. 

Tumor cells have a mucus (fibrin) coating that is designed to protect them from the body’s immune system.  This mucus coating works as a cloaking mechanism that prevents cancerous cells from being recognized by the immune system’s white blood cells thus making them immune to attack by natural killer cells. The sticky fibrin coating on cancerous cells is about 15 times thicker than the fibrin that surrounds healthy cells.

In the early 1900’s, Embryologist John Beard proposed that pancreatic proteolytic enzymes represent the body’s main defense against cancer, and that enzyme therapy would be useful as a treatment for all types of cancer. He theorized that if that protein layer could be dissolved, then the body’s normal defense systems such as the leukocytes (or white blood cells) would be able to destroy the cancerous cells. Beard tested his theory in 1911, and found that pancreatic enzymes had the ability to dissolve tumors in mice. Decades later, a Texas dentist by the name of Dr. William Donald Kelley read about the work of Dr Beard and then used high doses (50+ capsules per day) of pancreatic enzymes, a specialized diet of raw fruits and vegetables, grains and seeds, along with high doses of supplements, and detoxing therapies to cure himself from pancreatic cancer.

Metabolic typing–  After healing from cancer, Kelley began treating other people with a similar protocol but soon realized that people had individualized needs that needed to be addressed. It was then that he discovered the concept of Metabolic Typing- which recognizes that certain people have different requirements in regards to eating vegetarian or carnivorous diets, and whether their bodies did better when these foods were eaten raw or lightly cooked. Kelley then went on to treat and cure many people who were suffering from cancer using metabolic dietary principles, high doses of enzymes, supplements, and detoxing protocols.

Years later, Dr Nicholas Gonzales was asked to review the work of Dr Kelley while working on a postgraduate immunology fellowship. It was believed that the investigation would be used to discredit Dr Kelley, but Dr Gonzalez reports that he was very impressed with Kelley’s work, stating that Kelley had successfully cured many people from the most deadliest of cancers and he had kept detailed records to prove it.  Dr Gonzalez later resigned from his training position at Cornell University Medical College and began to practice his own version of metabolic dietary therapies that was based on the work of Dr Kelley.

There are two major classes of enzymes at work in the body:

  • Digestive- those that are used specifically in the digestive process.
  • Metabolic- enzymes responsible for building new cells and to repair damaged ones in the blood, tissues, and organs.

There are two types of oral enzyme therapies:

  1. Digestive- these are enzymes that are taken at mealtimes to assist in the break down of food and help with the absorption of nutrients.
  2. Systemic- these are larger doses that are taken away from mealtimes.  They are utilized by the body for various functions such as:
  • breaking down the fibrin proteins that surround tumors allowing them to be recognized and dissolved by the immune system.
  • enhance the ability of the immune cells to target and kill bacteria, viruses, molds, fungi, as well as cancerous cells.
  • dissolution of atherosclerotic plaques and clots without causing any harm to the arteries.
  • promotion of joint health by reducing inflammation which provides mobility and range of motion enhancement
  • dissolves scar tissue
  • aids in the detoxification of proteins
  • contributes to healthy aging by providing the body with an abundance of enzymes that are naturally declining as we age

Bromelain-  is a proteolytic enzyme found most abundantly in papaya and pineapples. It is especially concentrated in the core of the pineapple so be sure to run them through your juicer to capture the enzymes.  Bromelain supplements are inexpensive and can be used as a supportive adjunct to any other cancer treatment.

Serrapeptase -called Serratio Peptidase is another powerful proteolytic enzyme. It is produced by bacteria in the gut of silkworms and is used to digest their cocoons.  It is sometimes referred to as a “super enzyme” because of its ability to dissolve proteins, inflammations, scars, blood clots, cysts, and arterial plaque.

Pancreatic enzymes–  Dr. Nicholas Gonzalez (now deceased) and his partner Dr. Linda Isaacs practiced an enhanced version of Dr Kelley’s metabolic therapy at their New York clinic.  Dr Gonzalez passed away in 2015 but Dr Isaacs  continues to treat patients at the clinic.  High dose supplements and enzymes, specialized diets based on metabolic typing, and detoxification therapies remain the cornerstone of the treatments being offered there.  Patients are prescribed a variety of enzymes, including these Pancreatic Enzymes that were formulated with the assistance of Dr Gonzalez.  They are derived from a pig’s pancreas because it is very similar to a human pancreas, making it much more capable of dissolving the fibrin coating that surrounds tumors than vegetable derived enzymes. His patients would take 60+ pancreatic enzymes per day away from mealtimes. 

How to take high dose enzyme therapy:

  1. It is important to eat a diet that is high in raw fruits and vegetables that contain their own natural enzymes as the body will utilize them in the digestive process.
  2. Reduce or eliminate your intake of animal proteins as this will free up the metabolic enzymes to begin dissolving the  fibrin proteins throughout the body.
  3. Take proteolytic enzyme supplements on an empty stomach between mealtimes as this will allow them to be used therapeutically instead of being used for the digestion of food.
  4. Take 4-5 tablets upon waking, 4-6 one tablets hour before every meal, 4-6 tablets two hours after every meal, and an additional 4-6 tablets one hour before bedtime.

Contraindications –  consult with your health care provider if you are on blood thinners before starting this therapy.  Also take your time to build up to the larger doses.  It is possible that taking an excessive dose may lead to adverse effects in the form of digestive problems such as flatulence, gastric pain, and diarrhea which will disappear when the dosage is reduced.


Systemic enzymes and cancer part 1


part 2 on systemic enzymes and cancer


Additional Resources:

Read more about the work of Dr Nicholas Gonzalez and Dr Linda Isaac’s

Read more about enzyme rich foods

Systemic enzyme therapy

Enzyme therapy with bromelain

Q & A with Dr Nicholas Gonzalez regarding the nutritional, enzyme, and detox protocols

Read One Answer to Cancer by William Donald Kelley, DDS

Combine this therapy with a healing diet and lifestyle changes

Cancer is a wake up call which needs to be addressed on multiple fronts.   It is the end result of an overwhelmed and collapsed immune system due to eating nutritionally depleted foods, a build up of toxicity, and having poor lifestyle habits.   Research an anticancer diet, adding supplements, detoxing the body, and making lifestyle changes so you can address a cancerous situation with a multifaceted approach.

  Nutricology Pancreas, Natural Glandular (Pork), Capsules, 720-Capsules


  Enzymatic Therapy Mega-zyme, 200 Tablets


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